Subtext

Vertex Pharmaceuticals Incorporated VRTX

SectorHealth Care
Transcripts49
Date range2013-04-30 – 2025-05-05
Calls charted49

Sentiment timeline

Net Loughran-McDonald sentiment per call (×1000), earliest → latest.

-12-6+0+6+122013 Q12014 Q42016 Q32018 Q22020 Q12021 Q42023 Q32013 Q1 · Overall: -0.12013 Q2 · Overall: +3.32013 Q3 · Overall: -1.62013 Q4 · Overall: +2.62014 Q1 · Overall: +6.32014 Q2 · Overall: +7.22014 Q3 · Overall: +0.92014 Q4 · Overall: +1.72015 Q1 · Overall: -2.52015 Q2 · Overall: -0.12015 Q3 · Overall: +2.52015 Q4 · Overall: -2.52016 Q1 · Overall: -1.12016 Q2 · Overall: -3.22016 Q3 · Overall: +1.92016 Q4 · Overall: +2.42017 Q1 · Overall: +2.32017 Q2 · Overall: +3.12017 Q3 · Overall: +3.22017 Q4 · Overall: +2.42018 Q1 · Overall: +3.12018 Q2 · Overall: +5.62018 Q3 · Overall: +5.82018 Q4 · Overall: +6.62019 Q1 · Overall: +6.02019 Q2 · Overall: +6.42019 Q3 · Overall: +3.02019 Q4 · Overall: +5.52020 Q1 · Overall: +1.72020 Q2 · Overall: +2.92020 Q3 · Overall: +4.42020 Q4 · Overall: -0.62021 Q1 · Overall: +6.12021 Q2 · Overall: +7.62021 Q3 · Overall: +8.52021 Q4 · Overall: +3.02022 Q1 · Overall: +6.12022 Q2 · Overall: +8.72022 Q3 · Overall: +7.92022 Q4 · Overall: +7.92023 Q1 · Overall: +10.82023 Q2 · Overall: +9.32023 Q3 · Overall: +7.22023 Q4 · Overall: +9.02024 Q1 · Overall: +3.82024 Q2 · Overall: +5.92024 Q3 · Overall: +7.52024 Q4 · Overall: +6.42025 Q1 · Overall: +8.1
Overall

CEO vs CFO

Average sentiment of each executive's remarks per call. Divergence is a signal.

-50-25+0+25+502013 Q12014 Q42016 Q32018 Q22020 Q12021 Q42023 Q32013 Q1 · CEO: +2.92013 Q2 · CEO: +16.62013 Q3 · CEO: +4.82013 Q4 · CEO: +18.22014 Q1 · CEO: +8.32014 Q2 · CEO: +14.82014 Q3 · CEO: +11.62014 Q4 · CEO: +9.52015 Q4 · CEO: +6.72016 Q1 · CEO: +10.62016 Q3 · CEO: +3.72016 Q4 · CEO: +7.52017 Q1 · CEO: +10.72017 Q4 · CEO: +10.52018 Q3 · CEO: +4.82018 Q4 · CEO: +12.42019 Q1 · CEO: +12.52019 Q2 · CEO: +9.82019 Q3 · CEO: +16.12019 Q4 · CEO: +12.92020 Q4 · CEO: +2.02021 Q1 · CEO: +9.82021 Q2 · CEO: +13.52021 Q3 · CEO: +9.92021 Q4 · CEO: +2.22022 Q1 · CEO: +8.62022 Q2 · CEO: +9.62022 Q3 · CEO: +11.62022 Q4 · CEO: +11.92023 Q1 · CEO: +12.92023 Q2 · CEO: +11.42023 Q3 · CEO: +8.12023 Q4 · CEO: +8.72024 Q1 · CEO: +1.32024 Q2 · CEO: +7.12024 Q3 · CEO: +10.32024 Q4 · CEO: +6.02025 Q1 · CEO: +10.22013 Q1 · CFO: +0.62013 Q2 · CFO: +5.72013 Q3 · CFO: +3.52013 Q4 · CFO: +2.52014 Q1 · CFO: +11.82014 Q2 · CFO: +19.32014 Q3 · CFO: -3.32014 Q4 · CFO: +2.02015 Q1 · CFO: -19.92015 Q2 · CFO: +26.72015 Q4 · CFO: -7.22016 Q1 · CFO: -6.32016 Q3 · CFO: +2.42016 Q4 · CFO: +5.82017 Q4 · CFO: +15.22018 Q4 · CFO: +13.62019 Q1 · CFO: +26.52019 Q2 · CFO: +22.52019 Q3 · CFO: +6.52019 Q4 · CFO: +9.92020 Q4 · CFO: +13.42021 Q1 · CFO: +30.62021 Q2 · CFO: +21.42021 Q3 · CFO: +26.32021 Q4 · CFO: +28.92022 Q1 · CFO: +22.72022 Q2 · CFO: +23.12022 Q3 · CFO: +18.52022 Q4 · CFO: +19.22023 Q1 · CFO: +20.82023 Q2 · CFO: +22.72023 Q3 · CFO: +22.92023 Q4 · CFO: +16.22024 Q1 · CFO: +43.12024 Q2 · CFO: +11.22024 Q3 · CFO: +18.72024 Q4 · CFO: +18.82025 Q1 · CFO: +9.2
CEOCFO

Prepared remarks vs Q&A

Scripted tone vs unscripted answers. The gap is information.

-39-19+0+19+392013 Q12014 Q42016 Q32018 Q22020 Q12021 Q42023 Q32013 Q1 · Prepared remarks: +12.32013 Q2 · Prepared remarks: +10.42013 Q3 · Prepared remarks: +6.52013 Q4 · Prepared remarks: +16.42014 Q1 · Prepared remarks: +15.22014 Q2 · Prepared remarks: +20.52014 Q3 · Prepared remarks: +6.52014 Q4 · Prepared remarks: +9.52015 Q1 · Prepared remarks: +9.42015 Q2 · Prepared remarks: +7.42015 Q3 · Prepared remarks: +12.42015 Q4 · Prepared remarks: +8.22016 Q1 · Prepared remarks: +9.32016 Q2 · Prepared remarks: +14.22016 Q3 · Prepared remarks: +9.22016 Q4 · Prepared remarks: +5.82017 Q1 · Prepared remarks: +15.22017 Q2 · Prepared remarks: +7.42017 Q3 · Prepared remarks: +15.42017 Q4 · Prepared remarks: +6.02018 Q1 · Prepared remarks: +14.32018 Q2 · Prepared remarks: +10.82018 Q3 · Prepared remarks: +18.42018 Q4 · Prepared remarks: +16.32019 Q1 · Prepared remarks: +19.22019 Q2 · Prepared remarks: +23.12019 Q3 · Prepared remarks: +17.22019 Q4 · Prepared remarks: +17.12020 Q1 · Prepared remarks: +1.72020 Q2 · Prepared remarks: +2.92020 Q3 · Prepared remarks: +4.42020 Q4 · Prepared remarks: +9.12021 Q1 · Prepared remarks: +33.72021 Q2 · Prepared remarks: +20.22021 Q3 · Prepared remarks: +9.72021 Q4 · Prepared remarks: +13.02022 Q1 · Prepared remarks: +14.42022 Q2 · Prepared remarks: +15.12022 Q3 · Prepared remarks: +13.72022 Q4 · Prepared remarks: +13.02023 Q1 · Prepared remarks: +19.62023 Q2 · Prepared remarks: +14.32023 Q3 · Prepared remarks: +14.12023 Q4 · Prepared remarks: +14.42024 Q1 · Prepared remarks: +21.62024 Q2 · Prepared remarks: +12.62024 Q3 · Prepared remarks: +14.32024 Q4 · Prepared remarks: +13.32025 Q1 · Prepared remarks: +13.42013 Q1 · Q&A responses: -0.52013 Q2 · Q&A responses: +3.92013 Q3 · Q&A responses: -2.12013 Q4 · Q&A responses: -0.52014 Q1 · Q&A responses: +4.22014 Q2 · Q&A responses: +0.32014 Q3 · Q&A responses: +4.32014 Q4 · Q&A responses: +2.62015 Q1 · Q&A responses: -4.02015 Q2 · Q&A responses: +0.22015 Q3 · Q&A responses: -0.22015 Q4 · Q&A responses: -2.92016 Q1 · Q&A responses: -2.32016 Q2 · Q&A responses: -5.22016 Q3 · Q&A responses: +2.82016 Q4 · Q&A responses: +6.72017 Q1 · Q&A responses: +4.22017 Q2 · Q&A responses: +4.72017 Q3 · Q&A responses: +1.32017 Q4 · Q&A responses: +9.12018 Q1 · Q&A responses: +3.42018 Q2 · Q&A responses: +8.22018 Q3 · Q&A responses: +3.32018 Q4 · Q&A responses: +7.52019 Q1 · Q&A responses: +5.42019 Q2 · Q&A responses: +2.82019 Q3 · Q&A responses: -1.02019 Q4 · Q&A responses: +3.62020 Q4 · Q&A responses: +2.22021 Q1 · Q&A responses: +8.52021 Q2 · Q&A responses: +12.62021 Q3 · Q&A responses: +10.12021 Q4 · Q&A responses: +0.22022 Q1 · Q&A responses: +5.02022 Q2 · Q&A responses: +7.72022 Q3 · Q&A responses: +6.92022 Q4 · Q&A responses: +7.92023 Q1 · Q&A responses: +5.62023 Q2 · Q&A responses: +6.92023 Q3 · Q&A responses: +8.62023 Q4 · Q&A responses: +5.62024 Q1 · Q&A responses: +2.02024 Q2 · Q&A responses: +2.52024 Q3 · Q&A responses: +4.52024 Q4 · Q&A responses: +4.42025 Q1 · Q&A responses: +7.4
Prepared remarksQ&A responses

Tone vs forward expectations

Management tone next to Wall Street's forward-looking numbers (glopardo): the 12-month forward EPS estimate and the forward P/E per call.

Forward EPS estimate

$-3.04$8.06$19.162013 Q12014 Q42016 Q32018 Q22020 Q12021 Q42023 Q32014 Q1: $-1.512014 Q2: $-1.122014 Q3: $-0.632014 Q4: $-0.402015 Q1: $-0.142015 Q2: $1.932015 Q3: $2.772015 Q4: $3.482016 Q1: $2.902016 Q2: $2.272016 Q3: $2.502016 Q4: $2.342017 Q1: $1.962017 Q2: $2.392017 Q3: $2.812017 Q4: $2.932018 Q1: $3.402018 Q2: $3.882018 Q3: $4.472018 Q4: $4.232019 Q1: $4.632019 Q2: $5.212019 Q3: $5.772019 Q4: $6.692020 Q1: $8.322020 Q2: $9.952020 Q3: $10.952020 Q4: $11.522021 Q1: $11.662021 Q2: $11.712021 Q3: $12.922021 Q4: $13.442022 Q1: $14.392022 Q2: $14.812022 Q3: $15.152022 Q4: $15.882023 Q1: $14.582023 Q2: $15.282023 Q3: $15.842023 Q4: $16.352024 Q1: $17.132024 Q2: $17.622024 Q3: $13.38

Forward P/E

10.6539.4468.242013 Q12014 Q42016 Q32018 Q22020 Q12021 Q42023 Q32015 Q2: 64.272015 Q3: 48.302015 Q4: 34.062016 Q1: 27.302016 Q2: 40.112016 Q3: 36.082016 Q4: 33.472017 Q1: 48.252017 Q2: 52.182017 Q3: 55.852017 Q4: 49.422018 Q1: 51.252018 Q2: 39.212018 Q3: 39.532018 Q4: 37.512019 Q1: 40.062019 Q2: 34.882019 Q3: 30.232019 Q4: 32.792020 Q1: 25.592020 Q2: 28.162020 Q3: 24.442020 Q4: 20.152021 Q1: 18.622021 Q2: 16.012021 Q3: 14.622021 Q4: 15.712022 Q1: 17.272022 Q2: 17.112022 Q3: 18.802022 Q4: 19.652023 Q1: 20.192023 Q2: 22.322023 Q3: 21.892023 Q4: 24.772024 Q1: 24.122024 Q2: 26.512024 Q3: 35.42

Divergence watch ⚑

Quarters where tone and the forward EPS estimate moved opposite ways.

  • 2014 Q3 tone ↓ -6.3 fwd EPS ↑ +0.49 Tone cooled even as the forward EPS estimate rose.
  • 2015 Q1 tone ↓ -4.2 fwd EPS ↑ +0.26 Tone cooled even as the forward EPS estimate rose.
  • 2015 Q4 tone ↓ -5.0 fwd EPS ↑ +0.71 Tone cooled even as the forward EPS estimate rose.
  • 2019 Q3 tone ↓ -3.4 fwd EPS ↑ +0.56 Tone cooled even as the forward EPS estimate rose.
  • 2020 Q1 tone ↓ -3.8 fwd EPS ↑ +1.63 Tone cooled even as the forward EPS estimate rose.
  • 2020 Q4 tone ↓ -5.0 fwd EPS ↑ +0.57 Tone cooled even as the forward EPS estimate rose.
  • 2021 Q4 tone ↓ -5.5 fwd EPS ↑ +0.52 Tone cooled even as the forward EPS estimate rose.
  • 2023 Q1 tone ↑ +2.9 fwd EPS ↓ -1.30 Tone rose while the forward EPS estimate was cut.
  • 2023 Q3 tone ↓ -2.1 fwd EPS ↑ +0.57 Tone cooled even as the forward EPS estimate rose.
  • 2024 Q1 tone ↓ -5.3 fwd EPS ↑ +0.78 Tone cooled even as the forward EPS estimate rose.

Recent transcripts

CallDateSentiment ×1000Fwd EPSFwd P/E
2025 Q12025-05-05+8.1——View →
2024 Q42025-02-10+6.4——View →
2024 Q32024-11-04+7.5$13.3835.4View →
2024 Q22024-08-01+5.9$17.6226.5View →
2024 Q12024-05-06+3.8$17.1324.1View →
2023 Q42024-02-05+9.0$16.3524.8View →
2023 Q32023-11-06+7.2$15.8421.9View →
2023 Q22023-08-01+9.3$15.2822.3View →